Which type of skin cancer has a known potential to spread to lymph nodes?

The correct answer is melanoma, which is well-documented for its potential to metastasize, particularly to lymph nodes and other distant sites in the body. Melanoma arises from melanocytes, the pigment-producing cells in the skin, and has a propensity to invade deeper layers of the skin and surrounding tissues. This characteristic aggressive behavior often leads to the spread of cancerous cells through the lymphatic system, making it notable for lymph node involvement.

In contrast, basal cell carcinoma typically remains localized and rarely spreads to lymph nodes or other organs. It is the most common type of skin cancer and generally has a good prognosis due to its lower aggressiveness.

Squamous cell carcinoma does have a risk of metastasis; however, it is less likely to do so compared to melanoma. While it may invade locally and cause significant issues, its likelihood of spreading to lymph nodes is lower than that of melanoma.

Actinic keratosis is a precancerous condition rather than a true skin cancer. It can develop into squamous cell carcinoma but does not spread to lymph nodes on its own. It primarily presents as rough, scaly patches on sun-exposed skin and requires monitoring but is not inherently metastatic.

Thus, melanoma's established tendency to invade lymphatic tissue