Which part of the small intestine absorbs most nutrients post-digestion?

The jejunum is the part of the small intestine where the majority of nutrient absorption occurs after digestion. It follows the duodenum and precedes the ileum in the digestive tract. The structure of the jejunum—with its numerous villi and microvilli—increases the surface area, facilitating efficient absorption of nutrients, such as carbohydrates, proteins, vitamins, and minerals, into the bloodstream.

While the duodenum is primarily responsible for the initial phase of digestion and introduces enzymes and bile acids to aid in breaking down food, it does not absorb nutrients to the same extent as the jejunum. The ileum, while it does absorb certain nutrients, particularly vitamin B12 and bile salts, plays a secondary role relative to the jejunum when it comes to overall nutrient absorption. The colon is more involved in absorbing water and electrolytes and does not participate significantly in nutrient absorption.

Therefore, the jejunum is recognized as the most critical area for nutrient uptake following the digestion process in the small intestine.