Which of the following symptoms is NOT typically associated with hyperthyroidism?

In evaluating the symptoms typically associated with hyperthyroidism, it's essential to understand the underlying pathophysiology. Hyperthyroidism occurs when the thyroid gland produces excessive amounts of thyroid hormones, which accelerate various bodily functions.

Weight loss, increased appetite, and increased heart rate are all common manifestations of hyperthyroidism. Individuals may experience weight loss despite an increased appetite because the elevated levels of thyroid hormones boost metabolism and lead to the breakdown of proteins and fats. This metabolic increase can also result in a heightened heart rate, often referred to as tachycardia, as the body works more efficiently and vigorously.

In contrast, fatigue is not a typical symptom of hyperthyroidism. While some individuals might experience fatigue due to the strain on the body from the overstimulation of various systems, it is more commonly associated with hypothyroidism, where reduced thyroid hormone levels lead to a slowed metabolism and overall lethargy.

Therefore, understanding the symptoms associated with hyperthyroidism highlights that fatigue is typically not present in these patients, making it the correct choice as the symptom that is not commonly linked to this condition.