What is the primary indication of statins in clinical practice?

The primary indication of statins in clinical practice is to reduce cholesterol levels. Statins are a class of medications that inhibit HMG-CoA reductase, which plays a central role in the synthesis of cholesterol in the liver. By lowering the levels of low-density lipoprotein (LDL) cholesterol, statins help to decrease the risk of cardiovascular diseases such as heart attacks and strokes. They are particularly beneficial for patients with high cholesterol and those at risk for cardiovascular events because elevated LDL cholesterol is a significant risk factor for atherosclerosis, leading to these life-threatening conditions.

The other choices do not align with the primary function of statins; they do not manage blood pressure, increase blood sugar levels, or enhance kidney function directly. While modulating blood sugar and kidney function can be important in overall health management, they are not the main therapeutic goals of statin use.