What is a key difference between T cells and B cells in terms of attack strategies?

The key difference between T cells and B cells in their attack strategies primarily revolves around the types of pathogens they target and their mechanism of action. T cells, particularly cytotoxic T cells, are adept at identifying and attacking infected cells directly, making them particularly effective against viruses and some intracellular bacteria that replicate within the cells. This is crucial for eliminating pathogens that have already invaded host cells, where they cannot be detected by antibodies.

B cells, on the other hand, specialize in producing antibodies that target antigens present on the surface of pathogens such as bacteria and viruses that are outside the host cells. They are responsible for humoral immunity, where their antibodies bind to these invaders and facilitate their neutralization or destruction by other immune cells.

Given this context, stating that T cells attack invaders inside the cells while B cells focus on pathogens outside the cells accurately highlights their distinct roles in the immune response. This understanding is vital for comprehending how the adaptive immune system operates and the complementary functions of these two types of lymphocytes in protecting the body against infections.