What confirmatory test is commonly used to diagnose infectious mononucleosis?

The Monospot test is specifically designed to detect heterophile antibodies that are commonly present during infectious mononucleosis, particularly when caused by the Epstein-Barr virus (EBV). This test is quick and easy to perform, making it a preferred method in clinical settings for diagnosing this condition.

The Monospot test typically shows positive results within the first week of symptoms. In contrast, other tests like the ELISA can be used for more specific or confirmatory purposes but are not typically the first line of diagnosis in a suspected case of infectious mononucleosis. Western blot is a more complex test usually reserved for cases where definitive proof of EBV infection is needed or to diagnose other conditions. The hemagglutination test is not a standard confirmatory test for infectious mononucleosis and is more relevant in other contexts.

By using the Monospot test predominantly, physicians can quickly identify cases of infectious mononucleosis and proceed with appropriate management based on the presence of heterophile antibodies. The simplicity and reliability of the Monospot test make it the correct choice for this diagnosis.