Edward syndrome is associated with which trisomy?

Edward syndrome is specifically associated with Trisomy 18. This condition arises when an individual has three copies of chromosome 18, resulting in a range of developmental and physical abnormalities. Individuals with Edward syndrome often exhibit severe intellectual disability, distinct facial features, and various congenital malformations affecting several organ systems.

Emphasizing the characteristics that differentiate Trisomy 18 from the other trisomies is essential. Trisomy 21 is known as Down syndrome, characterized by a different set of phenotypic traits and health issues. Trisomy 13 is known as Patau syndrome, which has its specific clinical presentations distinct from those of Edward syndrome. Trisomy 16 typically leads to miscarriage before term and is not generally compatible with life when present in a live birth. Understanding these differences helps to solidify why Trisomy 18 is specifically linked to Edward syndrome.